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October 2015: IVF Retrieval #2 - 19 retrieved, 12 mature, 7 fertilize w/ICSI, 2 frozen, 1 normal. Jul 12, 2017 5:59 AM. Success rates present just one way of looking at PGS success. Preimplantation genetic testing is meant to tell you if your embryo has a specific genetic abnormality or not. All we can tell you is that this particular embryo has or doesnt have the condition. So here is what I will be taking. Hello, I am 35 and had 7 blastocyst sent to PGS and 3 came back normal. I wanted to point out thestandard deviationof this data is large, roughly 30% for each group. Women under the age of 34 are less likely to have a high percentage of eggs and embryos with abnormal chromosome counts. PGT is an optional test that can benefit women >35 years of age undergoing in vitro fertilization by avoiding the use of an aneuploid embryo. We sent in 8 for testing and only 2 came back normal. All were abnnormal with pgs. END MENTS We have 1 more normal embryo. In women under the age of 35, approximately 60% of embryos will be chromosomally normal. Your post will be hidden and deleted by moderators. The reason for the success, according to the clinic, is the perfection of the process. Diagnosis: Repeated Pregnancy Loss + DOR + Advance maternal Age. However, the classic Hamletian dilemma, 'to PGS or not to PGS', is not. I have sent 6 from 3 retrievals and only 1 was normal which we transferred one last week! I have done 4 IVF cycle and so far we had one normal from each cycle. Start discussing adoption immediately as I am assume I can't get pregnant at my age and because I have always had very irregular and infrequent cycles - will be diagnosed with PCOS in 2014. Aneuploidy in embryos by maternal age <25 - 36% 25-30 - 40% 31-34 - 43% 35-37 - 51% 38-40 - 64% 41-42 - 76% Chance of at least one normal embryo 25-30 - 91% 31-34 - 89% 35-37 - 83% 38-40 - 68% 41-42 - 51% 15 suran88 1 yr. ago Awesome Thank you so much for sharing this 2 chivy_2338 2 mo. Timing of ET: Transferring Blastocysts on Day 5-6 Post-Fertilization, Rather Than on Day 2-3 as Cleaved Embryos. In accordance with these findings, younger women are more likely to have at least one genetically normal embryo. / Jul 10, 2020. Aluko et al. Group Leaders arent expected to spend any additional time in the community, and are not held to a set schedule. 79% of the eggs studied from women 40-45 years old were found to have an abnormal spindle appearance and at least one chromosome displaced from proper alignment. This number indicates the blastocyst development stage or the degree of the expansion of the embryo's cavity. Also, keep in mind that pregnancy rates will also depend on the overall egg quality of the eggs retrieved during one . I have one left so still hoping for a happy ending. At my age, I was told 1:4 would be normal, but my results were 1:6.5. If the embryo is missing a chromosome and has 45, this is known as monosomy. It was certainly disappointing. CoQ10 Ubiquinol not Ubiquinone. In a woman under age 30, about half of embryos are aneuploid. Does it still matter? However, Dr Esteves cautioned that other factors might also affect the likelihood of obtaining a normal embryo. I got the call this morning that How many FETs with PGS embryos before pregnancy/live birth? Preimplantation genetic testing for aneuploidy versus morphology as selection criteria for single frozen-thawed embryo transfer in good-prognosis patients: a multicenter randomized clinical trial. What Is PGT-A or PGS Genetic Screening? For <37, this was about 5, for 37-40 about 4, and for >40 about 3 (so older women tend to produce fewerblasts). Since we have been performing PGT-A on blastocysts (day 5 or 6 embryos) at our Newport Beach fertility center, we have found the accuracy of the procedure to be greatly improved. As the chart below shows, a relatively small percentage of embryos developed during IVF qualify as "chromosomally-normal" or "euploid." 'Here we are considering women's age only.'. Of those 7, 3 were abnormal, 4 were considered chromosomally normal. We see the doc on Monday so I'll be really interested to know what was "abnormal" about the other 6. The blast was hatching at transfer. The day following your retrieval, we will check to see if fertilization successfully took place. It had an extra chromosome from the sperm and another from the egg. If you want to read more about about success rates for untested embryos, go to my embryo grading and success rates post. Well also look at the chances of getting a euploid based on age, the impact of embryo grade and the day it was frozen (Day 5, 6 or 7), and how rebiopsies or thaw and biopsies fare for success rates. ***tw*** we transferred one, and I'm 14 weeks along. What Research Shows, What Is IVF Success Rate? Your eggs will be fertilized with sperm on that day. IVF with PGS/PGD results in a lower number of miscarriages than without it (from 9-10% lower with PGS to 38% lower with PGD). Check out mycomplete guide to embryo grading and success ratesto learn more about embryo development, grading and success rates. Once the follicles in the ovaries are mature and the eggs are ready to be harvested, fertility doctors retrieve eggs carefully. Newport Beach, California 92663. Create an account or log in to participate. This includes preeclampsia and other hypertensive disorders, and possibly small for gestational age fetuses. Obviously this is not an ideal situation but sometimes this happens. PGT does not guarantee that you have healthy embryos. 2018). We sent in 8 for testing and only 2 came back normal. Risk Factors that Impact IVF with PGS Success Rates. We have decided to do one more round of IVF but first I'm going to try improving my egg quality naturally for the next few weeks. PGT cannot detect autism because it is not caused by a single gene mutation or a chromosomal numerical abnormality. The graph below illustrates what we have discovered. Start taking baby aspirin. On average, women in their late 20s had four euploid embryos (day 3 or day 5) per cycle, but this number decreased linearly (R2 R 0.983) after 35 years of age. If you get a mosaic embryo, your clinic may or may not recommend transferring this embryo depending on your situation. This can be done! Theper retrievalstatistic helps to see the chancesbefore PGStesting. He also answers questions in his private Facebook group. FET July 2012-BFN. We were shocked that this could happen at age 32 with no explanation. If autism is present in your family it is important to get a genetic carrier screening test to look for other conditions you might carry in your DNA. In a study analyzing 4,515 patients with up to three consecutive Single Embryo Transfers (SET) of chromosomally normal, or euploid, embryos, 94.9% achieved a pregnancy. Dr wants to first get 2-3 PGS normal embryos before doing immune testing. In these women, it is thought that other genetic factors other than chromosome number also affect the embryo and hence pregnancy as the egg cell ages. Implantation Failure in IVF - Why Does It Happen? Continuing with the normal IVF process, an embryologist fertilizes the egg with sperm collected from the womans partner or with donor sperm. Oftentimes, we will recommend that you see a genetic counselor to understand the risks involved with using a mosaic. Not exactly! He is a Fellow of the American College of Obstetricians and Gynecologists and Member of the American Society for Reproductive Medicine. I will definitely share in the forum any updates. (2018)found a slight reduction inlive birth ratecompared to single biopsied embryos (50% vs 58%), but this was notstatistically significant. 1. We had 6 out of 10 retrieved make it to day 5/6. After age 35, the average number of euploid embryos decreased sharply, with a strong inverse linear relationship with age in both day-3 and day-5 embryos (R 2 = 0.983 and 0.991, respectively; Fig. Then I opened my eyes and researched them extensively and spoke to specialists and came to the conclusion that PGS may only be good for those who have a known family genetic abnormalities. FZMM 5 yr. ago The study analyzed more than 46,000 embryos between 2009 and 2014. PGS results take between 10-14 days after the embryo biopsy is taken. All tests normal. I can't help but think about all these moms that got zero normal results and their story could have turned out like yours. Embryoman (Sean Lauber) is a former embryologist and creator of Remembryo.com. So far no luck with IVF attempts. ago Hi! DH and I have talked about it and honestly I don't care either way. If an embryo has an X and a Y chromosome, it is a male. May 1st- blood test come back positive for hyperthyroidism. Unfortunately, chromosomally abnormal eggs will develop into chromosomally abnormal embryos following fertilization. Second round we had 15 eggs, 13 were mature and ICSI, 9 fertilized, we had 1 5 day hatching blast that we transferred (BFN), and then 1 day 6 blast. What percentage of PGS embryos are normal? Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. I wish you tons of baby dust!!! For example, some cells appear chromosomally normal, while others showed some form of aneuploidy. (2017)had similar results to above (aCGH, women <35): Capalbo et al. We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. About Us---- Advertise ---- Contact Us ---- Privacy Policy ---- Terms of Use. Chromosomal abnormalities occur more often than people think. PGS and IVF success Chromosomal abnormalities in embryos are common. One clinic determined IVF with PGS success rates to have a 10% higher pregnancy rate. I know how hard it is. If an embryo has two X chromosomes, it is a female. We have 13 fertilized growing right now. He has a special interest in health, lifestyle, & nutrition. I am thankful i did not transfer. We retrieved 19, 17 fertilized and 10 made it to day 5. Embryos end up with an abnormal number of chromosomes because the egg has abnormal chromosomes, or the sperm has abnormal chromosomes or during the first cell division after fertilization, the chromosomes are inappropriately separated. Bleeding During IVF - What's Normal and What Isn't? Doctors also prescribe medication to women to suppression ovulation. Unfortunately, this embryo split and I miscarried at 7.5 weeks. think twice before sharing personal details, foster a friendly and supportive environment, remove fake accounts, spam and misinformation, delete posts that violate our community guidelines, reviewed by our medical review board and team of experts. I'm now extremely worried that neither of the 2 stick because DH won't agree to another round and I desperately want this baby! To see a fertility specialist with a high success rate using single embryo transfer, make an appointment at one of InVia's four Chicago area fertility clinics. 10 Important Factors To Consider, IVF Success Rates Over 40 with Own Eggs and Donor Eggs, Male factor infertility IVF success rates. (2016)looked at over 18,000 Day 5 embryo biopsies (usingthe older SNP technology) and reported the chances of an embryo beingeuploid(based on age): So up until 37 theres about a 50% chance of each blastocyst being a euploid, this cuts in half to about 25% at 42. Meaning that if you begin a cycle, retrieve eggs, produce embryos, then do PGS testing, and at least one embryo comes back normal, 60 70% of the time it will lead to a live birth. I went to a good clinic in Toronto. Our results from PGT-A are even better than we initially expected. So most <35 women are between 30-90% chance ofeuploid(61% is the average). Nearly 60% are over 42 and nearly half are over 44. For a fresh cycle with PGT to identify chromosome number abnormalities, the pregnancy rate is 68 percent. Typically, only genetically normal embryos will be kept for transfer. My doctor does not believe I have PCOS. started June 26th. I just expected better results. 2. We had transferred one, the ended in a CP. Use our. These forums were a critical source of support when we were in the midst of fertility treatments, and even now as I struggle with accepting that it is over. For some women going through IVF, the choice of having PGS performed on their embryos is a no-brainer. So those 2 could have been normal but they didn't get a reading on them. https://alexroblesmd.com/wp-content/cache/breeze-minification/js/breeze_d8b9ac1cac0e674c1a0b0961093927ba.js, https://alexroblesmd.com/wp-content/cache/breeze-minification/js/breeze_e709f6277bbec007e5a021ac9cdc419b.js, https://alexroblesmd.com/wp-content/cache/breeze-minification/js/breeze_d6638419dc0ffa7ebd981022572d700a.js, https://alexroblesmd.com/wp-content/cache/breeze-minification/js/breeze_b410f7096d4a966b622520512b7f5e7d.js. 1: Early blastocystthe blastocele is less than half the volume of the embryo. However, we have also realized that there is even more genetic abnormality in eggs that we previously thought. We added 12 hours of progesterone. I'm now awaiting results curious finding out your numbers how many were normal that were tested and what the gender was if you found out? October 8th, thyroid is now fine. Preliminary studies examine the rebiopsy and transfer of chaotic embryos by PGT-A. The effect of maternal age on the possibility of retrieving at least one normal embryo was similar, with a rapid exponential decline (R2 14 0.986). December 2015: IVF Retrieval #3 - 31 retrieved, 24 mature, 21 fertilized w/ICSI, 8 frozen, 3 normal. The presence of an abnormal number of chromosomes in the genetic profile of early-stage embryos may be far more common and potentially less threatening during normal human development than is currently believed, according to new research from Johns Hopkins University biologists. IVFauthority.com does not provide medical advice. As PGT-A tests for the number of chromosomes in an embryo's cells and the identity of each chromosome, the results can identify embryo's affected by Down Syndrome. Results from PGS demonstrated that the average blastocyst euploid rates across all age groups on days 5, 6, and 7 were 49.5, 36.5, and 32.9%, respectively. At InVia Fertility Specialists, we have been offering SMART IVF (PGD or PGS) for many years. Sadly all mine came at the end. I have been in the Nutraceutical Industry for over 20 yrs and very familiar with most supplements. Our second and last IVF we just got one blastocyst as well and are waiting for our PGS results. . In round 2, 1 of the 2 was normal, and round 3, 3 of the 8 were normal. Wish I read it long before my first cycle. Hi everyone, we just got PGS results back and I'm a bit shocked. Most clinics now believe that transferring better-developed embryos - i.e. (2018)found a reduction in clinical pregnancy when embryos were thawed, biopsied and re-frozen (the odds were about half). Yes, it happened to us. Appointment on June 20th, 2013. This is a fancy way of saying, does the embryo contain the correct number of chromosomes? Nov-Dec 2015: Freak out that out of almost 50 eggs, only 1, 1! The simple answer is, we really don't. The likelihood an embryo will successfully implant is about 46% for women under age 35, according to national averages from over 400 IVF clinics in the U.S. For women within ages 38 to 40, those implantation chances drop to 28% and at ages 41 to 42, less than 18% of embryos will successfully implant. For more background info, check out my post onPGS Testing. Starting our IVF journey and we are having a hard time making some decisions. Transferring an embryo after a PGT-A test, therefore, reduces miscarriage and improves pregnancy rates per embryo transferred. Doug Donovan. Although I am a physician by profession, I am not YOUR physician. Blood tests at the end of July and end of August to see if all is well. For more than a decade, we have been screening embryos for chromosomal number abnormalities (aneuploidy) at InVia Fertility Specialists. . Most places allow up to 8 blasts to be tested for the the same price (but you have to pay for each IVF cycle obviously). We sent the 3 blasts together for PGS and none of them were normal which was heartbreaking. Infertility issues are so heartbreaking already! During this process, as many eggs as possible will be collected. Neal et al. As expected, the percentage of women with at least one normal embryo declines with increasing age. Hopefully, one or more embryos will make it to the blastocyst stage on Days 5, 6, or 7. PMID: 30246223; PMCID: PMC6338591. So in some ways, it is futile to compare IVF with PGS success rates to IVF without it, because chromosomally abnormal embryos do not have the same chances of success. Some women do a few banking cycles if you can afford it. I'm so sorry it happened to you. PGD 2 out of 11 embryos are normal and put back in. Now, I can't source that, but it was something one of the REs that did an AMA on here said - maybe Dr. Aimee? Thanks for your encouragement! The rate of aneuploidy begins to increase significantly after the age of 40 and drops below 30% in women over the age of 41. I have some immune issues related to my losses I think so I'm betting the doctor would recommend putting a girl embie back in first. Your embryos will then be kept in the IVF lab for one week. Increasing maternal age is associated with decreasing egg quality. FET#2 July 2017 - BFP. (2014)found no difference inongoing pregnancieswith Day 5 or 6 euploids (about 50%). The PGT biopsy is a fairly safe procedure when done on blastocyst embryos. We have to know the specific condition that we are looking for to be able to do PGT-M. Lastly, PGT-SR can test for larger genetic abnormalities like Robertsonian translocations or chromosomal inversions. More studies need to be done. The maximum post-PGS live birth rate for women younger than 35 is 60%. We sent 8 to be PGS tested and 7 came back normal. Implantation, or pregnancy, rates were highest for the first transfer for a euploid embryo: it stood at 69.4%. In all those success rate there will always be a 20%, 30%, 40% chance of failure, that may have nothing to do with anything. IVF#2 Fall 2012 Those clinics may specialize in IVF and PGS/PGD, and it is worth looking into how a clinic performs the screening. We expected to have at least one. April 4th 2013. By the time a woman reaches 40, about 10-15% of her eggs are chromosomally normal. All three were boys. Another concern is the accuracy rate, which is approximately 98%. Make sure you buy a brand that you see that uses Kaneka material (it'll reference it on the back of bottle) as that is the one with studies some others are Chinese and it is not the same. I called the place that did my PGS even and asked percentages of what strands were abnormal in the cell lines. My Dr says at my age about 75% will be abnormal. *Note: PGS stands for preimplantation genetic screening. Learn more about. Hey Peg, Third one in the past few months doing a medicated cycle. Save my name, email, and website in this browser for the next time I comment. This article provides an overview of IVF withPGS/PGD success rates. Based on our most recent PGS data for 2018, women in the age category of 38-40 had an 82% chance of pregnancy with a PGS Cycle. We do have one normal PGS tested frozen embryo from prior cycle. Success rates for frozen embryo transfer after PGT. So in the end 3 of 15 were normal - pretty much bang on the stats. Chances for getting a euploid embryo A recent 2019 study looked at 130,000 biopsies by NGS tested (this is the current testing method): Donor eggs: 63.1% euploid <35 years: 59.5% euploid 35-37 years: 50.3% euploid 38-40 years: 38.3% euploid 41-42 years: 26.8% euploid 43-44 years: 24% euploid Damaged embryos may not implant, or could ultimately result in irreparable harm leading to miscarriage and IVF failure. Long story short we transferred our so called "abnormal" boy this past March and I am currently 24 weeks pregnant with a NORMAL HEALTHY baby boy!! And so many stories of success, I feel greatly relieved. Congratulations on your pregnancy! The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. The embryo having an abnormal chromosome number. This is because PGT-A/PGS is not a one hundred percent test, however most of the labs that are carrying out PGT-A with NGS have a very high diagnostic rate so most of the time you have a very good . But actually, it would be 3/7 that were normal, according to how the stats are actually calculated - those that didn't make it to blast were abnormal, most likely. Your clinic may have a better idea of how things work in their hands. 2 5-day blasts transferred (Assisted Hatching -AH used). For simplicity's sake, if 12 mature eggs are usually enough for one normal embryo, which has a good chance (65 percent) of leading to a pregnancy, 24 mature eggs would be a good number for a woman who wants two children. Embryo screening may improve success rates. Transfers using excellent grade blastocysts have a pregnancy rates of about 65%. Referral to endocrinologist. Always consult your physician in the area for your particular needs and circumstances prior to making any decisions whatsoever. My husband and I are both 34. If it contains an extra chromosome and has 47, this is known as a trisomy. (2017)found no difference in survival rates of embryos that were thawed and biopsied, then refrozen. 10 mature. They found a reduction in live birth rates (50% to 39%), although this was notstatistically significant(it was from a small study). 2011(38) : Get married and our son is born. Factors that can influence treatment costs include: Patients often hear PGS-normal embryos have a 60 70% success rate. I had 30 eggs, 21 mature, 20 fertilized, 8 made it to blast (6 of them on day 5 and 2 on day 6). PGS was developed to address what has been one of the greatest challenges in ART, the inability of embryologists to identify chromosomally normal (euploid) embryos for transfer into the woman's uterus in an IVF cycle. However, mosaic embryos do have as high of live birth rates compared to euploid embryos. Start avoiding phalates, eating more plant-based proteins, and doing anything else I can find, legitimate or not, that promises to increase egg quality. As of right now, the exact cause of autism is unknown and thought to be due to multiple factors. What percentage of embryos come back PGS normal? March 2017. We sent 11 for testing and 6 came back normal. Past protocols were simply based on the appearance of the embryos. And I hope your babies are super sticky too :) Congrats on BFP!!! eggs will be fertilized with sperm on that day, make it to the blastocyst stage on Days 5, 6, or 7. I also try to buy the Jarrow brand as I worked for them up to last Sept before I quit to prep for IVF process. Congratulations, that's such a heartwarming story. For women over 40 years old, the pregnancy rate decreases to 55 percent. We had a total of 10 after my IVF. Most of our embryos do not. They also provided information for the chance of getting no euploids per cycle: So as age increases, the chances of getting a euploid embryo drop. I was one month shy of 39 at retrieval. I am sure I will still have my moments of sadness, but I do really want to be a parent. However, a larger biopsy is taken, it can potentially harm the embryo. April 2011 Consult with RE. Therefore, an embryo with 46 chromosomes is called a euploid embryo and is considered normal. We sent the best 8 for testing. Not all will autocorrect but right now enough research is being done on the mosaic monosomies that is proving many are viable embryo transfers. For an embryo to lead to a healthy, live birth, it must have the proper number of chromosomes. Four were Day 5 and one was Day 6. I knew I could easily donate normal embryos but with all the negatives people give to abnormal embryos no one would want them. Being 37 and based on those stats I was expecting 4-5, not the 22% we got. Inconclusive or No Result biopsies may require a second round of biopsy aka a rebiopsy. What is a Good First hCG Level after Embryo Transfer? IVF involves several different types of tests, screenings, and procedures in order to increase the likelihood of success. Having a euploid embryo does not guarantee a live birth. As women age, the likelihood of an irregular chromosome count only increases. 2019 Jan;36(1):165-172. doi: 10.1007/s10815-018-1322-2. PGS is also known as pre-implantation genetic testing for an aneuploidy (PGT-A). What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. The most common scale uses a number and two letters to describe each embryo ('4AB' for example). 2: Blastocystthe blastocele is greater than or equal to half of the volume of the embryo. Good luck to you!! 3 failed IUIs, May 2015: IVF#1 - 29 retrieved, 19 mature, 10 fertilized. Twins & Multiples: Your Tentative Time Table. Please re-enable javascript to access full functionality. Most of us have 46 chromosomes. Thank you for answering :) wishing you baby dust! Although I strive to provide accurate general information, the information presented here isnot intended for the prevention or treatment of infertility and it isnot a substitute formedical or professional advice. This is because chromosomally abnormal embryos are more likely to arrest during early development compared to chromosomally normal embryos At age 42, around 80% of embryos are aneuploid. Abnormal embryos, called aneuploid, would not have this normal complement of chromosomes. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. There was also no difference with Day 7, although the sample size was very small. Logic suggests that by implanting embryos that are known to be normal, the likelihood of miscarriage or failed implantation goes down. Now we have one PGS tested embryo left and I'm devastated. Meaning that if you begin a cycle, retrieve eggs, produce embryos, then do PGS testing, and at least one embryo comes back normal, 60 70% of the time it will lead to a live birth. Further testing - the RPL test- results in suspected immune issues. The PGS/PGD results determine whether or not an embryo has a normal number of chromosomes. Another small study found no difference in survival or live birth rates with rebiopsied embryos (Cimadomo et al. Also now we know some things we should work on to increase our chances for the second round. An average IVF cycle lasts between 8-12 days. By age 40, almost 60% of her remaining eggs are abnormal, and by age 44, that percentage climbs to almost 90%. The live birth rate declines to 55% for women ages 35 to 40. Thats a major benefit and source of assurance to women who have suffered many miscarriages prior to IVF with PGS. However, almost all studies and clinic data show that IVF success rates indicates higher pregnancy rates. Your chances are good with two normal embryos! Out of any normals, we will take the doctors advice on what to use first. The term "recurrent miscarriage" means at least two consecutive pregnancies ended prematurely; this affects between 1% and 3% of all women. When looking at IVF success rates, its important to consider all of the success metrics, not just miscarriage rates. qs. (2016)found nostatistically significantdifference inongoing pregnanciesbetween Day 5 and 6 euploids (78.6% vs 67.4%), but this was reduced by Day 7 (43.8%). By being careful and selective in choosing with embryos to transfer, a clinic can dramatically increase the likelihood of success. Recommended protocol to take baby aspirin. IVF#2- Sept 2016 (Freeze all/PGS). Success with PGS normal embryos- how many tries? What percentage of PGS embryos are normal? Some clinics in US report success rates upwards of 75% pregnancy and live births, even for women well into their 40s. Younger women and couples with no likelihood of carrying genetic abnormalities typically do not choose PGS/PGD. For now its probably best to avoid having to thaw and biopsy if possible. As the bar graph demonstrates, over 75% of CHR's IVF patients are over 40. Your clinic may have a better idea! But in hindsight I should realize that stats are the average of both extremes. I have an older son so I wouldn't mind using an ed. 2019 Dec;112(6):1071-1079.e7. In two of these embryos all reanalysed cells were normal diploid, i.e. We had 9 eggs, 7 fertilized, 3 made it to freeze. Of these, 11 (34%) had a successful pregnancy with apparently healthy babies born. The graph below shows the percentage of genetically normal eggs of women in various age groups. We are considering doing another round but are not sure. This allows doctors to time IVF treatment precisely, and to schedule an appointment to retrieve eggs, rather than letting the body ovulate and release just one egg (which is what normally happens).